The greatest burden of all is the sin that separates us from God, leading to bondage, separation, and eternal death. This burden is deceptive, as people may appear to be doing well but are actually living under the wrath of God. The consequences of sin include bondage, separation from God, and eternal death, which is the second death, cast into the lake of fire. The judgment of the wicked is about the degree of punishment for all eternity, not about salvation.
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